Endocrine Abstracts

Objective: Gestational thyroid dysfunction and gestational diabetes mellitus (GDM) are common complications during pregnancy and often co-occur. Since thyroid hormones increase glucose uptake and insulin sensitivity, it has been hypothesized that hypothyroidism might increase the risk of GDM. Our aim was to study if maternal thyroid function test abnormalities are risk factors for GDM.Methods: A systematic search of Ovid MEDLINE, EMBASE and Web of Scienc...

Objective: Adequate thyroid hormone availability is essential for foetal neurodevelopment. While overt maternal hypothyroidism is associated with lower offspring IQ, recent studies suggested an inverse U-shaped association, with suboptimal offspring neurodevelopment for both the lower and higher thyroid function range. Our aim is to investigate the association of gestational thyroid function with offspring IQ scores, assess if this association is different based on the gestati...